Wire the motion sensors in rooms and in between rooms in a series circuit and connect the sensors on all the doors and windows in a parallel circuit.
The reasoning being, if you open a window or door the sensors will trip and the circuit will break if the sensors are wired in series, however, if the sensors are connected in parallel the sensors can be opened and the alarm system will not stop working. By connecting the stationary sensors in series, you will prevent people from disconnecting these sensors without the alarm going off.